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KALA | 多肽 | MCE

KALA | 多肽 | MCE

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Peptides

KALA

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KALA 

目录号: HY-P2530

纯度: 96.09%

FAQs

Data Sheet

SDS

COA

产品使用攻略

溶解度

摩尔计算器

动物溶解计划

KALA 是一种在生理 pH 下构成 α-螺旋结构的两亲性肽。KALA 润饰了包裹质粒 DNA 的脂质体膜，也能够用作交融肽，经过半乳糖完结有用的肝靶向和受体转染 DNA。

MCE 的一切产品仅用作科学研讨或药证申报，咱们不为任何个人用处供给产品和服务

Custom Peptide Synthesis

KALA Chemical Structure

CAS No. : 187987-64-0

1.  客户无需承当相应的运送费用。

2.  同一组织（单位）同一产品试用装仅限申领一次，同一组织（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

标准

价格

是否有货

数量

1 mg

￥2500

In-stock

0

1

2

3

4

5

6

7

5 mg

￥7500

In-stock

0

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2

3

4

5

6

7

10 mg

询价

50 mg

询价

or

大包装询价

* Please select Quantity before adding items.

KALA 相关抗体

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KALA 相关产品

•相关化合物库:

Bioactive Compound Library Plus

Peptide Library

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生物活性

纯度 & 产品资料

参考文献

生物活性

KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors[1].

体外研讨(In Vitro)

When a plasmid DNA-encapsulating liposomal membrane is modified with the KALA peptide, transgene expression and immune activation are facilitated in bone marrow-derived dendritic cells (BMDCs)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

KALA 相关抗体:

Clinical Trial

分子量

3131.82

Formula

C144H248N40O35S

CAS 号

187987-64-0

性状

固体

色彩

White to off-white

Sequence

Trp-Glu-Ala-Lys-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Ala-Lys-His-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Lys-Ala-Cys-Glu-Ala

Sequence Shortening

WEAKLAKALAKALAKHLAKALAKALKACEA

运送条件

Room temperature in continental US; may vary elsewhere.

贮存方法

Sealed storage, away from moisture and light, under nitrogen

Powder

-80°C

2 years

-20°C

1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility

In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

Contents

Assign value

Acidic amino acid

Asp (D), Glu (E), and the C-terminal -COOH.

-1

Basic amino acid

Arg (R), Lys (K), His (H), and the N-terminal -NH2

+1

Neutral amino acid

Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)

0

3.  Recommended solution:

Overall charge of peptide

Details

Negative (<0)

1.  Try to dissolve the peptide in water first.

2.  If water fails, add NH4OH (<50 μL).

3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.

Positive (>0)

1.  Try to dissolve the peptide in water first.

2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.

3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.

Zero (=0)

1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.

2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

纯度 & 产品资料

纯度: 96.09%

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